A sprained ankle will keep Cleveland Cavaliers shooting guard Dion Waiters out of Monday's game against the Detroit Pistons, Mary Schmitt Boyer of The Plain Dealer reports. The rookie suffered the injury in the fourth quarter of Saturday night's game against the Portland Trail Blazers.

After an MRI confirmed the ankle sprain, the team listed Waiters as "questionable" for Monday's game, but he apparently hasn't responded quick enough to treatment. The soonest he could return is Wednesday, when the Cavaliers return home to host the Chicago Bulls.

Over 17 games this season, Waiters has averaged 32 minutes per game, a rather high amount for a rookie that had been coming off the bench in college. Per game, he's averaging 15.2 points, 3.4 assists and 1.2 steals, though he's also taking shots at a higher rate than anyone on the team not named Kyrie Irving.

It's unclear who is starting in Waiters' place, but Daniel Gibson, C.J. Miles and Omri Casspi would seem to be possibilities.