In Cleveland's win, Jackson recorded nine tackles -- while forcing one fumble and recovering another -- as the Browns forced Pittsburgh to commit eight turnovers.
Cleveland's front seven held the Steelers to just 49 rushing yards, which is the fewest amount of rushing yards allowed by the Browns since 2003.
The award marks the first time Jackson has been named Defensive Player of the Week in his career. Jackson, who turned 29 in September, has recorded 84 tackles on the season, while registering three sucks, forcing two fumbles and recovering two fumbles. Jackson has also intercepted a pass that he returned for a touchdown.
Jackson will have an opportunity to earn his second Defensive Player of the Week award this week, when the Browns head to Oakland to take on the Raiders in Week 13.